Buckinghamshire Hospitals NHS Trust was established in April 2003 with the formal merger of South Buckinghamshire NHS Trust and Stoke Mandeville Hospital NHS Trust.

The Trust serves residents in Buckinghamshire, Thame (Oxfordshire), Tring (Hertfordshire) and Leighton Buzzard (Bedfordshire) - a combined population of 500,000. It serves a much larger population of 1.5m for Burns and Plastic Services and 14m for Spinal Injuries.

Three Primary Care Trusts are responsible for commissioning healthcare for this population (except for Bedfordshire and Hertfordshire patients): Vale of Aylesbury PCT; Chiltern and South Bucks PCT; and Wycombe PCT.

There are three hospitals in the Trust - Amersham Hospital (Situated on the edge of historic Amersham Old Town close to major road links to Wycombe, Aylesbury and M25), Stoke Mandeville Hospital (Situated on the edge of the market town of Aylesbury with major road links to London and Oxford) and Wycombe Hospital (A busy town centre general hospital, again with excellent major road links to London and the M25. The Trust currently has 4,700 staff.